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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DCLK2 All Species: 21.82
Human Site: S385 Identified Species: 48
UniProt: Q8N568 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N568 NP_001035350.2 766 83612 S385 G V N G N R C S E S S T L L E
Chimpanzee Pan troglodytes XP_001150968 766 83601 S385 G V N G N R C S E S S T L L E
Rhesus Macaque Macaca mulatta XP_001082020 783 85228 S402 G V N G N R C S E S S T L L E
Dog Lupus familis XP_539760 862 93767 S402 G V N G N R C S E S S T L L E
Cat Felis silvestris
Mouse Mus musculus Q6PGN3 756 82960 S384 G V N G N R C S E S F P L L E
Rat Rattus norvegicus Q5MPA9 767 83998 S400 G V N G N R C S E S F T L L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511279 630 68724 A285 R S T G K E F A L K I I D K A
Chicken Gallus gallus XP_420439 761 82932 G383 V N G N K C S G S S T I L E K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001139259 791 87409 R390 S P E V N G N R N L A A S T I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394386 670 74883 H325 R L H Y A V G H V I G E G N F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001189418 661 74296 N316 L P K T V P V N G S P T A T R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 96.4 81.9 N.A. 93.4 92.6 N.A. 71 84.5 N.A. 71.5 N.A. N.A. 39.5 N.A. 48.6
Protein Similarity: 100 99.4 97 83.9 N.A. 95.4 95 N.A. 75.7 89.9 N.A. 82.4 N.A. N.A. 57 N.A. 62.1
P-Site Identity: 100 100 100 100 N.A. 86.6 93.3 N.A. 6.6 13.3 N.A. 6.6 N.A. N.A. 0 N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 86.6 93.3 N.A. 13.3 26.6 N.A. 13.3 N.A. N.A. 13.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 0 10 0 0 10 10 10 0 10 % A
% Cys: 0 0 0 0 0 10 55 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % D
% Glu: 0 0 10 0 0 10 0 0 55 0 0 10 0 10 55 % E
% Phe: 0 0 0 0 0 0 10 0 0 0 19 0 0 0 10 % F
% Gly: 55 0 10 64 0 10 10 10 10 0 10 0 10 0 0 % G
% His: 0 0 10 0 0 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 10 10 19 0 0 10 % I
% Lys: 0 0 10 0 19 0 0 0 0 10 0 0 0 10 10 % K
% Leu: 10 10 0 0 0 0 0 0 10 10 0 0 64 55 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 55 10 64 0 10 10 10 0 0 0 0 10 0 % N
% Pro: 0 19 0 0 0 10 0 0 0 0 10 10 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 19 0 0 0 0 55 0 10 0 0 0 0 0 0 10 % R
% Ser: 10 10 0 0 0 0 10 55 10 73 37 0 10 0 0 % S
% Thr: 0 0 10 10 0 0 0 0 0 0 10 55 0 19 0 % T
% Val: 10 55 0 10 10 10 10 0 10 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _